With Reactive it's really easy to set multiple delivery zones. You can use zones to set different shipping costs for different areas. 

Go to Settings > Shipping methods. Click the "Create" button at the top of your screen to create a new shipping method or edit an existing one by clicking the pen icon. 

To create a new delivery zone simply click on the "Add new" button.

Select the countries and regions you wish your products to be delivered. If you don' t want to define shipping zones, then your products will be available for sale in all countries.

Note: Customers can order products from your store only if the country or region where they want the order shipped to is included in one of your shipping zones.

Once you have created your zone click the save button at the top of your screen.